Xanthogranulomatous gastritis: Associatlion with xanthogranulomatous cholecystitis

A case of xanthogranulomatous inflammation of the gastric wall is reported. The lesion was associated with adherent xanthogranulomatous cholecystitis and simulated, clinically, a malignant neoplasm. Histologically, foamy histiocytes, multinucleated giant cells, other inflammatory cells, fibrous reaction with spindle cells and cholesterol clefts were found. (7 Clin Pathol 1993;46:88-90) Xanthogranulomatous inflammation is characterised by varying amounts of foamy histiocytes, inflammatory cells, fibrous reaction and sometimes multinucleated giant cells. Typically, the process causes destruction and effacement of the normal structures of the affected organ and may simulate a neoplasm.' We report an unusual xanthogranulomatous process of the gastric wall in a patient with xanthogranulomatous cholecystitis. To the best of our knowledge a similar case has not been reported before.